Martinos Center researcher Randy L. Buckner, PhD, and colleagues have provided direct support for a third somatomotor map in the vermis of the cerebellum by using intensive, repeated functional MRI scanning of individuals performing movements across multiple body parts.
Caterina Mainero, MD, PhD, director of the Multiple Sclerosis Imaging Laboratory in the Martinos Center for Biomedical Imaging, discusses the lab’s research into the mechanisms of the disease and new approaches to diagnosis and monitoring.
The Martinos Center’s Caterina Mainero, MD, PhD and colleagues reviewed the interplay of fibrinogen and coagulation factors with neuroinflammation in multiple sclerosis. They conclude that basic knowledge of the coagulation pathways could be translated into new treatment approaches and novel diagnostic and prognostic biomarkers.
A study by the Martinos Center’s Leo Cheng, PhD and colleagues suggests that metabolomic changes detected with an advanced nuclear magnetic resonance (NMR) spectroscopy technique can differentiate between patients with benign prostate biopsies who will or will not receive a prostate cancer diagnosis over the following years.
Michael Lu, MD, MPH, Vineet Raghu, PhD and colleagues have developed a deep learning model that can predict the 10-year risk of death from a heart attack or stroke using a single chest X-ray.
Jyrki Ahveninen, PhD and colleagues believe sparse brain activity, where only a few neurons in a population fire at a given time, might contribute to the fingerprint patterns of activity evident in multi-voxel pattern analysis results from functional MRI — and give rise to perceptual, emotional and cognitive functions.